Sex Hormone Binding Globulin (SHBG)

Test Code

CPT Codes

Preferred Specimen
0.7 mL serum

Minimum Volume
0.5 mL

Transport Container
Plastic screw-cap vial

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Immunoassay (IA)

Setup Schedule
Set up: Daily evening; Report available: Same day

Reference Range
<3 Years Not established  
   Male  Female
3-9 Years  32-158 nmol/L 32-158 nmol/L
10-13 Years 20-166 nmol/L 24-120 nmol/L
14-17 Years 20-87 nmol/L 12-150 nmol/L
18-55 Years 10-50 nmol/L 17-124 nmol/L
>55 Years 22-77 nmol/L 14-73 nmol/L

Clinical Significance
Testosterone, dihydrotestosterone and estrogens circulate in serum bound to Sex Hormone Binding Globulin (SHBG). SHBG concentrations are increased in pregnancy, hyperthyroidism, cirrhosis, oral estrogen administration and by certain drugs. Concentrations are decreased by testosterone, hypothyroidism, Cushings syndrome, acromegaly and obesity.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.