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5-HIAA, Plasma
Test CodeMISC1
Preferred Specimen
1 mL plasma collected in a heparin (green-top) tube or EDTA (lavender-top) tube
Patient Preparation
Avoid bananas, avocados, plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for 72-hour period prior to and during collection. Plasma must be separated from cells within 45 minutes of venipuncture.
Minimum Volume
0.5 mL
Instructions
Send plasma in plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Temperature
Frozen
Specimen Stability
Room temperature: 72 hours
Refrigerated: 72 hours
Frozen: 14 days
Refrigerated: 72 hours
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
High-Pressure Liquid Chromatography (HPLC)/Tandem Mass Spectrometry
Setup Schedule
Set up: Once a week; Report available: 8-15 days
Clinical Significance
Plasma 5-hydroxy-indoleacetic acid (5HIAA or 5-HIAA) is a metabolite of serotonin that can be elevated as a result of carcinoid tumors/carcinoid syndrome.
