A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Aldosterone, Response to ACTH Stimulation, LC/MS/MS
Test CodeALDOSRAS
Quest Code
17832
CPT Codes
82088 (x2)
Includes
Aldosterone, Baseline
Aldosterone, 60 minutes
Aldosterone, 60 minutes
Preferred Specimen
1 mL serum collected in each of two red-top tubes (no gel)
Minimum Volume
0.25 mL (x2)
Other Acceptable Specimens
1 mL plasma collected in each of two EDTA (lavender-top) tubes, sodium heparin (green-top) tubes, or lithium heparin (green-top) tubes
Instructions
Draw baseline specimen. Draw another specimen 60 minutes after stimulation. Serum separator tubes are unacceptable. Draw blood in a no-additive (red-top) tube. Separate serum after clotting. Ship serum refrigerated (cold packs) or frozen. Do not submit glass tubes. Draw "upright" samples at least 1/2 hour after patient sits up.
Note: Cortrosyn (cosyntropin) not supplied by the laboratory. This test cannot be collected at a Patient Service Center.
Note: Cortrosyn (cosyntropin) not supplied by the laboratory. This test cannot be collected at a Patient Service Center.
Transport Temperature
Serum: Frozen
Plasma: Room temperature
Plasma: Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tubes • Moderate to gross hemolysis
Methodology
Liquid Chromatography Tandem Mass Spectrometry (LC/MS/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Monday-Friday, Sunday Night
Report available: 3 Days
Report available: 3 Days
Reference Range
See Laboratory Report
Clinical Significance
Approximately 1-2% of individuals with primary hypertension have primary hyperaldosteronism characterized by hypokalemia (low potassium) and low direct renin. Because serum aldosterone concentrations vary due to dietary sodium intake and body position, some physicians prefer measurement of 24-hour urine concentrations for aldosterone.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |
Last Updated: June 8, 2023