Phosphorylated Tau 181 (pTau-181), Plasma

Message
ORDER AS A MISCELLANEOUS TEST


Test Code
483745 (LABCORP)


CPT Codes
83520

Preferred Specimen
1 mL EDTA Plasma


Patient Preparation
his test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.

Minimum Volume
0.7 mL (Note: This volume does not allow for repeat testing.)


Transport Temperature
Room Temperature


Specimen Stability

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days



Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples must be labeled with complete first and last name
Samples must be labeled with date of birth


Report Available
1-3 days


Limitations

This test  was developed and its performance characteristics determined by Labcorp.  It has not been cleared or approved by the Food and Drug Administration.



This test is performed by Roche Diagnostics Electrochemiluminescence Immunoassay (ECLIA). Values obtained with different assay methods or kits cannot be used interchangeably.



Hepatic and renal function impact concentrations of pTau-181.1,2



Results of plasma pTau-181 testing in patients with a history of myocardial infarction (MI) or clinical stroke should be interpreted with caution.2




Performing Laboratory
LabCorp


Last Updated: December 27, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.