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Smooth Muscle Antibody with Reflex to Titer
Test CodeSMAT
Quest Code
263
CPT Codes
86015
Includes
If Smooth Muscle Antibody Screen is positive, then Smooth Muscle Antibody Titer will be performed at an additional charge (CPT code(s): 86015).
Preferred Specimen
0.5 mL serum
Minimum Volume
0.1 mL
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic
Methodology
Immunofluorescent Assay (IFA)
Setup Schedule
Set up: Mon, Tues, Thurs-Sat; Report available: 3-4 days
Reference Range
Negative
Clinical Significance
Smooth muscle antibodies are detected in 85% of patients with chronic active hepatitis and in less than 50% of patients with primary biliary cirrhosis. Smooth muscle antibodies are usually negative in extrahepatic biliary obstruction, drug induced liver disease, viral hepatitis and hepatoma.
Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Last Updated: March 29, 2023