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VDRL Titer, Spinal Fluid
MessageOrder as MISC VDSFQ
Test Code
VDRL Titer, CSF
Alias/See Also
VDSFQ
Preferred Specimen
CSF only
Minimum Volume
0.5 mL
Instructions
Only orderable as a reflex. For more information see VDSF / VDRL, Spinal Fluid.
Transport Container
Sterile Vial
Specimen Stability
Frozen (Preferred) 14 days
Refrigerated 14 days
Refrigerated 14 days
Methodology
Flocculation/Agglutination
Setup Schedule
Monday, Wednesday, Friday
Report Available
1-3 days
Reference Range
Negative
CAUTIONS
VDRL testing on spinal fluid gives a high percentage of false-negative results.
Clinical Significance
VDRL is a nontreponemal serologic test for syphilis that uses a cardiolipin-cholesterol-lecithin antigen to detect reaginic antibodies.
The presence of neurosyphilis in untreated patients can be detected by the presence of pleocytosis, elevated protein, and a positive VDRL.
The presence of neurosyphilis in untreated patients can be detected by the presence of pleocytosis, elevated protein, and a positive VDRL.
Performing Laboratory
Mayo Clinic Laboratories
3050 Superior Drive NW
Rochester, MN 55901
Last Updated: December 27, 2023
