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BCR/ABL1 t(9;22)
Message- Note; Please exclude biopsy needles, blades, and other foreign objects from transport tubes. These can compromise specimen viability and yield, and create hazards for employees.
Test Code
BCRABLFISH
Alias/See Also
NEO BCR ABL FISH TRANSLOC 9 22
Philadelphia Chromosome
Philadelphia Translocation
QUEST TC# 12070
Includes
Probes: ABL1 (9q34); ASS1 (9q34; BCR (22q11.2)
Disease(s): CML, ALL, MPN
Note: For suspected ALL, STAT processing is available by request. Note STAT along with MD contact name and phone number to receive STAT results.
Preferred Specimen
- Bone Marrow Aspirate: 1-2mL Sodium Heparin Tube. EDTA tube is acceptable
- Peripheral Blood: 2-5mL Sodium Heparin Tube. EDTA tube is acceptable
- Fresh, Unfixed Tissue: Tissue in RPMI
- Fluids; Equal parts RPMI to specimen volume.Paraffin or Cut Slides: N/A
Transport Temperature
Refrigerate specimen. Do not freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen.
Methodology
FISH
Report Available
3-5 days. STAT results, when requested, are reported 12-24 hours from receipt in the NeoGenomics laboratory.
Clinical Significance
Translocation 9;22 is seen in chronic myelogenous leukemia and acute lymphoblastic leukemia.
Performing Laboratory
NEOGenomics
9490 Neo Genomics Way
Fort Myers, FL 33912
Last Updated: September 13, 2022
