GAD65, IA-2, and Insulin Autoantibody

Test Code

GAD65IA2INS

Quest Code

10584

CPT Codes
86337, 86341 (x2)

Includes

Glutamic Acid Decarboxylase-65 Antibody
IA-2 Antibody
Insulin Autoantibody

Preferred Specimen

2 mL serum

Minimum Volume

0.4 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Enzyme Linked Immunosorbent Assay (ELISA) • Radiobinding Assay (RBA)

Setup Schedule

Set up and Report available: See individual tests

Limitations

GAD-65 antibodies are detected in 20% of diabetic twins who remain disease-free for long periods of time and in 8% of healthy individuals.

Reference Range

GAD-65 Antibody	<5 IU/mL
IA-2 Antibody	<5.4 U/mL
Insulin Autoantibody	<0.4 U/mL

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: April 19, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.