Prostaglandins D2, Serum or Plasma

Test Code

63282

CPT Codes
84150<br /> **This test is not available for New York patient testing.**

Preferred Specimen

3 mL serum collected in a red-top tube (no gel)

Patient Preparation
Patient should not be on aspirin, indomethacin, or anti-inflammatory medications, if possible, for at least 48 hours prior to collection of specimen.

Minimum Volume

1 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube

Instructions

Serum or EDTA plasma should be collected and separated as soon as possible. Freeze specimen immediately after separation. Ship specimens frozen on dry ice.

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Methodology
Radioimmunoassay (RIA)

Setup Schedule

Set up: Set up on weekdays as needed (no specific days); Report available: 10-12 days

Reference Range

See Laboratory Report

Clinical Significance

Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.

Performing Laboratory
Inter Science Institute
944 W Hyde Park Blvd
Inglewood, CA 90302

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.