Everolimus, LC/MS/MS, Blood

Test Code

18883

Alias/See Also

Afinitor
18883

CPT Codes
80169

Preferred Specimen

2 mL whole blood collected in an EDTA (lavender-top) tube

Minimum Volume

1 mL

Instructions

Drug regimens are to be noted on requisition: Time and date of drug administration.
Note: Therapeutic range applies to trough specimens drawn just prior to a.m. dose.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gel barrier tubes • Clotted specimens

Methodology
Chromatography/Mass Spectrometry

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Reference Range

Trough	3.0-8.0 ng/mL for Transplantation
Trough	5.0-10.0 ng/mL for Oncology/Neurology

Symptoms of toxicity are more likely to occur at trough levels exceeding 12.0 ng/mL

Clinical Significance

Everolimus is an immunosuppresive drug used in organ transplantation to prevent graft rejection. Therapeutic drug monitoring is useful to optimize dose and avoid toxicity.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: June 10, 2022

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.