BioFire Meningitis PCR

CSFPCR

CSF for Bio FIre Panel
Multiplex PCR
Meningitis
Encephalitis

Rapid detection of meningitis and encephalitis caused by:
-Escherichia coli K1 (K1 serotype only)
-Haemophilus influenzae
-Listeria monocytogenes
-Neisseria meningitidis (encapsulated strains only)
-Streptococcus agalactiae (Group B Strep)
-Streptococcus pneumoniae
-Cytomegalovirus (CMV)
-Enterovirus -Herpes simplex virus 1 (HSV-1)
-Herpes simplex virus 2 (HSV-2)
-Herpes simplex virus 6 (HHV-6)
-Human parechovirus -Varicella zoster virus (VZV)
-Cryptococcus neoformans/gattii
This test is not intended for use with CSF collected from indwelling medical devices (eg, CSF shunts). This test is not recommended as a test of cure.

1 mL CSF in sterile fluid

0.5 mL

Room Temp: 1 day
Refrigerate: 7 days
Frozen: Not acceptable.

Samples not labeled with complete first and last name and date of birth.
Specimen in transport media.
Centrifuged shunt fluid

Daily

1 day

Specimen must arrive at refrigerated temperature within 7 days of collection

Negative

Clinical Significance. Meningoencephalitis (Encephalitis) Panel, CSF - This panel may assist in identifying infectious agents causing encephalitis or meningoencephalitis. It is a qualitative multiplex nucleic acid-based test that detects and identifies bacterial, viral and yeast DNA/RNA directly from a single aliquot of cerebrospinal fluid (CSF). The meningitis/encephalitis panel is NOT a replacement for CSF bacterial and/or fungal culture and Cryptococcal antigen testing for at-risk patients. Non-K1 E. coli serotypes and non-encapsulated strains of Neisseria meningitidis are NOT detected. The panel does NOT differentiate active from latent herpes virus infections.