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Hepatitis A IgM Antibody
Test CodeHAVM
CPT Codes
86709
Preferred Specimen
1.0 mL Serum or Plasma
Minimum Volume
50 uL
Other Acceptable Specimens
Plasma- Lithium Heparin (PST),
Sodium Heparin
Plasma- EDTA (Lavender)
Serum- Red Top
Gold Top (SST)
Tiger Top (SST)
Sodium Heparin
Plasma- EDTA (Lavender)
Serum- Red Top
Gold Top (SST)
Tiger Top (SST)
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 2 hours at 20-25 deg C
Refrigerated: 7 days at 2-8 deg C
Frozen: 3 months at -20 deg C
Timing Considerations: Serum and plasma should be separated from the cells within 2 hours from the time of collection.
Refrigerated: 7 days at 2-8 deg C
Frozen: 3 months at -20 deg C
Timing Considerations: Serum and plasma should be separated from the cells within 2 hours from the time of collection.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples not labeled with complete first and last name and date of birth.
Grossly hemolyzed.
Grossly hemolyzed.
Methodology
Electrochemiluminescence immunoassay
Setup Schedule
Sun - Sat
Report Available
Same day
Reference Range
Non-reactive
Clinical Significance
The assay is intended for use as an aid in the laboratory diagnosis of an acute or recently acquired hepatitis A virus infection. Assay results, in conjunction with other laboratory results and clinical information, may be used to provide presumptive evidence of infection with hepatitis A virus in persons with signs and symptoms of hepatitis and in persons at risk for hepatitis A infection.
The hepatitis A virus is a RNA containing virus that lacks an envelope. It belongs to the family of picornaviruses. To date, just one human serotype and 7 genotypes have been described. The viral capsid consists of 3 proteins (VP1 VP3) that form an immunodominant structure on the surface of the viral particle that is highly conserved between all genotypes. After vaccination or natural infection, the immune response is directed against this structure.
Hepatitis A is the most common form of acute viral hepatitis. It is transmitted by the fecal-oral route. The disease has not been known to take a chronic course, nor does the virus persist in the organism. An acute or recently acquired hepatitis A infection can be assumed if anti HAV IgM antibodies are detected. Anti HAV IgM antibodies can always be detected at the onset of the disease, and usually disappear 3 to 4 months later. Anti HAV IgM can also be detected in some patients for a longer period of time, however. HAV IgM antibodies develop only very rarely after vaccination.
The hepatitis A virus is a RNA containing virus that lacks an envelope. It belongs to the family of picornaviruses. To date, just one human serotype and 7 genotypes have been described. The viral capsid consists of 3 proteins (VP1 VP3) that form an immunodominant structure on the surface of the viral particle that is highly conserved between all genotypes. After vaccination or natural infection, the immune response is directed against this structure.
Hepatitis A is the most common form of acute viral hepatitis. It is transmitted by the fecal-oral route. The disease has not been known to take a chronic course, nor does the virus persist in the organism. An acute or recently acquired hepatitis A infection can be assumed if anti HAV IgM antibodies are detected. Anti HAV IgM antibodies can always be detected at the onset of the disease, and usually disappear 3 to 4 months later. Anti HAV IgM can also be detected in some patients for a longer period of time, however. HAV IgM antibodies develop only very rarely after vaccination.
Performing Laboratory
Frederick Health Laboratory
400 W 7th St
Frederick, MD 21701
Last Updated: December 28, 2023
