Copeptin

Test Code

COPEP

Quest Code

37740

Alias/See Also

37740
ADH
Anti-Diuretic Hormone

CPT Codes
86255

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube or sodium heparin (green-top) tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis

Methodology
Immunofluorescence Assay (IFA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon, Wed, Sat; Report available: 3-5 days

Reference Range

0-2 Years	Not Established
3-17 Years	2.4-26.0 pmol/L
≥18 Years	≤13.7 pmol/L

Clinical Significance

The Copeptin test is used in the diagnosis of central diabetes insipidus and in the differential diagnosis of central or nephrogenic diabetes insipidus. It is a reliable surrogate marker for arginine vasopressin (AVP).

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: January 2, 2020

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.