Transferrin, Carbohydrate-deficient (Alcohol Use)

Test Code

16985

Alias/See Also

Carbohydrate-deficient Transferrin
CDT
Transferrin, COOH-deficient

CPT Codes
82373, 84466

Includes

CDT
Transferrin
% CDT

Preferred Specimen

1 mL serum

Patient Preparation
Fasting preferred

Minimum Volume

0.5 mL

Instructions

Serum samples must be fully coagulated, centrifuged within 1 hour of collection, and must not contain any particles or traces of fibrin after centrifugation. Transfer serum to a clean, plastic, screw-cap vial.

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Nephelometry

Setup Schedule

Set up: Mon-Sat p.m.; Report available: Next day

Reference Range

CDT	28.1-76.0 mg/L
Transferrin	188-341 mg/dL
% CDT	<2.5 %

Clinical Significance

Heavy alcohol use (defined as >4 or 5 beverages per day for two weeks or more) is commonly associated with elevated CDT levels as are certain liver diseases such as primary biliary cirrhosis and chronic active hepatitis and in some patients with genetic D variants of transferrin.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

Last Updated: November 18, 2022

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.