CAH Panel 4 (17-Hydroxylase Deficiency in Females)

Test Code

CAH Panel, Females

Quest Code

15274

Alias/See Also

17-Hydroxylase Deficiency in Females

CPT Codes
84144, 83498, 82528, 82533, 82088, 82670

Includes

Aldosterone, LC/MS/MS
Corticosterone
Cortisol, Total, LC/MS
Estradiol, Ultrasensitive, LC/MS
7-Hydroxyprogesterone
Progesterone, LC/MS

Preferred Specimen

3 mL serum collected in a red-top tube (no gel)

Patient Preparation
An early morning specimen is preferred

Minimum Volume

1.2 mL

Instructions

Collect blood in a Vacutainer with no additives. Allow blood to clot (10-15 minutes) at room temperature. Centrifuge and separate the serum from the cells.

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tubes • Moderate to gross hemolysis • Received room temperature • Grossly icteric • Glass tubes

Methodology
Extraction • Immunoassay (IA) • Chromatography/Mass Spectrometry

Setup Schedule

Set up and Report available: Varies with assay

Reference Range

See Laboratory Report

Clinical Significance

All steroids requiring the action of 17-Hydroxylase enzyme are low, including 17-OH Progesterone and Cortisol. Levels of estradiol and aldosterone are also low. Additional testing may be required to establish a diagnosis.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: August 16, 2019

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.