Chromosome Analysis, Blood with reflex to Postnatal ClariSure® Oligo-SNP Array

Test Code

Chromosome Analysis, Blood with reflex

Quest Code

18980

CPT Codes
88230, 88262

Includes

If Chromosome analysis is normal, then Chromosomal Microarray, Postnatal, ClariSure® Oligo-SNP will be performed at an additional charge (CPT code(s): 81229)

Preferred Specimen

10 mL whole blood collected in a sodium heparin (green-top) tube

Minimum Volume

5 mL

Other Acceptable Specimens

Whole blood collected in a: sodium heparin (royal blue-top), or sodium heparin lead-free (tan-top) tube

Instructions

Clinical history/reason for referral is required with test order.

Ship at room temperature. Specimen viability decreases during transit. Do not freeze. Do not reject.

Preliminary results available for neonatal specimens three days after receipt.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Preferred
Refrigerated: Acceptable
Frozen: Unacceptable

Methodology
Culture • Karyotype • Microscopy

Reflex: Oligo-SNP Array

Setup Schedule

Set up: Daily; Report available: Chromosome reports 10 days, and array reports 7 days later if needed

Reference Range

See Laboratory Report

Clinical Significance

Chromosome analysis can be used to help determine genetic causes of intellectual disability, developmental delay, congenital anomalies, infertility, miscarriage, stillbirth, and ambiguous genitalia. Chromosome analysis does not rule out cryptic or submicroscopic chromosome abnormalities. If this analysis is normal, microarray will be performed for the detection of submicroscopic deletions and duplications and long continuous regions of homozygosity.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: August 13, 2019

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.