TORCH PANEL, CONVALESCENT

Test Code

TORCHCONV

Quest Code

10010

Alias/See Also

TORCH IgG
TORCH Prenatal

CPT Codes
86644, 86695, 86696, 86762, 86777

Includes

Toxoplasma Antibody (IgG) with Reflex to Toxoplasma Antibody (IgM)
Rubella Antibody (IgG), Immune Status
Cytomegalovirus Antibody (IgG)
Herpes Simplex Virus 1 and 2 (IgG), Type-Specific Antibodies

If Toxoplasma IgG Antibody is ≥0.91, then Toxoplasma IgM Antibody will be performed at an additional charge (CPT code(s): 86778).

Preferred Specimen

2.5 mL serum

Minimum Volume

1.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Icteric • Plasma • Cord blood

Methodology
See individual tests

Setup Schedule

Set up: Mon, Wed, Fri; Report available: 1-4 days

Reference Range

See Laboratory Report

Clinical Significance

This panel may provide antibody-based evidence of a recent or previous infection with Toxoplasma gondii, rubella virus, cytomegalovirus, and/or herpes simplex virus in pregnant individuals. This panel is generally ordered as part of a prenatal evaluation of a patient who is at risk of infection with these microbial agents. However, routine serology testing for these infections as a group has low diagnostic yield for non-specific ultrasound abnormalities of fetuses [1,2].

Some maternal infections during pregnancy may be associated with miscarriage, stillbirth, or fetal abnormalities.These infections may be primary (ie, occur for the first time) or the result of reactivation of prior infections (eg, herpes simplex virus or cytomegalovirus). Infections with these pathogens may have a subclinical course in the mother and transmit to the infant during the prenatal or perinatal period [3].

Testing for infections in pregnant persons should be guided by pathogen-specific clinical features, risk factors, and prevalence [1]. The American Academy of Pediatrics Committee on Fetus and Newborn and American College of Obstetricians and Gynecologists Committee on Obstetric Practice recommend serologic screening for evidence of rubella immunity at the first prenatal visit [3]. Routine serologic screening of pregnant individuals for Toxoplasma and cytomegalovirus is not recommended [3]. Type-specific serologic testing for herpes simplex virus may be useful in the evaluation of risk for infection or confirmation of suspected infection [3,4].

This panel is not recommended for use in documenting newborn congenital infections. In this clinical situation, consider requesting the Torch Panel, Acute.

The results of this test panel should be interpreted in the context of pertinent clinical findings.

References
1. Fitzpatrick D, et al. Prenat Diagn. 2022;42(1):87-96.
2. Society for Maternal-Fetal Medicine (SMFM), et al. Am J Obstet Gynecol. 2020;223(4):B2-B17.
3. American Academy of Pediatrics Committee on Fetus and Newborn and American College of Obstetricians and Gynecologists Committee on Obstetric Practice. Guidelines for Perinatal Care. 8th ed. 2017. Accessed April 28, 2022. https://www.acog.org/clinical-information/physician-faqs/-/media/3a22e153b67446a6b31fb051e469187c.ashx
4. Workowski KA, et al. MMWR Recomm Rep. 2021;70(4):1-187.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: September 8, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.