Platelet Antibody, Direct (IgG)

Test Code
APLTD


Quest Code
91740


CPT Codes
86023<br /> **This test is not available for New York patient testing**

Preferred Specimen
10 mL whole blood collected in an ACD solution A (yellow-top) tube


Minimum Volume
5 mL


Other Acceptable Specimens
Whole blood collected in: ACD solution B (yellow-top) tube


Instructions
Collect 10 mL of whole blood in ACD (yellow-top) tube. Transport at room temperature immediately after
collection.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 72 hours
Refrigerated: Unacceptable
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Lipemia • Clotted specimens • Received refrigerated • Received frozen • Icteric


Methodology
Flow Cytometry (FC)

FDA Status
This test was developed and its performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. Performance characteristics refer to the analytical performance of the test.

Setup Schedule
Set up: Daily; Report available: 3-4 days


Reference Range
Negative


Clinical Significance
Platelet associated IgG, IgA, and IgM (PAIgG, PAIgM, PAIgA) detection is useful in identifying immune-mediated platelet destruction. Elevated PAIgG is associated with autoimmune thrombocytopenia purpura (ITP) as well as thrombocytopenia in systemic lupus erythromatous (SLE), carcinoma, HIV, lymphoma, Hodgkin's disease and Hashimoto's thyroiditis.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: July 20, 2018


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.