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Methylmalonic Acid, GC/MS/MS, Random Urine
MessageOrder MMA24U for a 24 hr urine.
Test Code
MMARU
Quest Code
91032
Alias/See Also
Methylmalonic Acid 24 hr urine
Methylmalonic Acid random urine
Methylmalonic Acid random urine
CPT Codes
82570, 83921
Preferred Specimen
1.7 mL of an unpreserved random urine submitted in a plastic leak-proof container
Minimum Volume
0.6 mL
Other Acceptable Specimens
Unpreserved, catheterized urine, or first void clean catch urine, or random clean catch urine or 24-hour urine
Instructions
Do not use preservatives
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 4 days
Refrigerated: 12 days
Frozen (-20° C): 30 days
Frozen (-70° C): 90 days
Refrigerated: 12 days
Frozen (-20° C): 30 days
Frozen (-70° C): 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Acidified urine
Methodology
Chromatography/Mass Spectrometry
Setup Schedule
Set up: Tues, Fri; Report available: 4 days
Reference Range
| Methylmalonic Acid, Urine | 0.3-2.2 mmol/mol creat |
Creatinine, Random Urine
| 0-6 Months | 0.18-2.48 mmol/L |
| 7-11 Months | 0.18-2.74 mmol/L |
| 1-2 Years | 0.18-9.72 mmol/L |
| 3-8 Years | 0.18-11.49 mmol/L |
| 9-12 Years | 0.18-14.14 mmol/L |
| >12 Years | 1.77-23.31 mmol/L |
Clinical Significance
Methylmalonic Acid (MMA) is useful to diagnose and monitor Vitamin B12 (cobalamin) deficiency, and to diagnose and monitor patients with methylmalonic acidemia.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Last Updated: December 21, 2021
