Albumin, 24-Hour Urine with Creatinine

Test Code

MALB24HCREA

Quest Code

15281

CPT Codes
82043, 82570

Includes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen

5 mL urine aliquot from a well-mixed 24-hour urine collection submitted in a plastic leak-proof container - no preservative

Minimum Volume

2 mL

Other Acceptable Specimens

Urinalysis transport tube (yellow-top, blue fill line, preservative tube)

Instructions

Specify 24-hour total volume on container and test requisition.

Note: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Acid preserved urine

Methodology
Turbidometric

Setup Schedule

Set up: Daily; Report available: 1 day

Reference Range

Albumin, 24 hour urine	<30 mg/24 h
Albumin, 24 hour urine	<20 mcg/min

Creatinine, 24-Hour Urine

<3 Years	Not established
3-8 Years	0.10-0.80 g/24 h
9-12 Years	0.20-1.40 g/24 h
13-17 Years	0.40-1.90 g/24 h
>17 Years	0.50-2.15 g/24 h

The ADA defines abnormalities in albumin excretion as follows:

Category	Result (mg/24 h)	Result (mcg/min)
Normal	<30	<20
Microalbuminuria	30-299	20-199
Clinical Albuminuria	≥300	≥200

The ADA recommends that at least two of three specimens collected within a 3-6 month period be abnormal before considering a patient to be within a diagnostic category.

Clinical Significance

Albumin excreted in the urine (Microalbumin) is a sensitive marker of Nephropathy. It is used to screen for early renal disease in diabetic patients.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

Last Updated: April 10, 2018

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.