Cardiolipin Antibody (IgG)

Test Code

ACARDIGG

Quest Code

4662

CPT Codes
86147

Preferred Specimen

1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube

Minimum Volume

0.5 mL

Other Acceptable Specimens

1 mL serum

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 5 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Tues-Sat; Report available: 3-5 days

Reference Range

Value	Interpretation
<20.0 GPL-U/mL	Antibody not detected
≥20.0 GPL-U/mL	Antibody detected

Clinical Significance

Cardiolipin antibodies (CA) are seen in a subgroup of patients with autoimmune disorders, particularly Systemic Lupus Erythematosus (SLE), who are at risk for vascular thrombosis, thrombocytopenia, cerebral infarct and/or recurrent spontaneous abortion. Elevations of CA associated with increased risk have also been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, and primary Sjögren's syndrome.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

Last Updated: March 26, 2018

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.