Blood Urea Nitrogen

BUN

Urea Nitrogen

1.0 mL plasma collected in a PST (LiHeparin tube)

0.5 mL

Plasma - EDTA (Lavender Top)

Serum- SST (Red Top  or Tiger Top)
Urine - Sterile Cup, B-D urine foley and BD specimen cup collection kit.  May be random or 24-hr collection.  No preservative needed.

Room Temperature: Plasma \Serum 7 days at 15-25°C Urine 2 days at 15-25°C Refrigerated: Plasma \Serum 7 days at 2-8°C Urine 7 days at 2-8°C Frozen: Plasma/Serum 1 year at -20°C Urine 1 months at -20°C

Grossly Hemolyzed, Lipemic, and Icteric are unacceptable.
Samples not labeled with complete first name, last name, and date of birth.

Mon-Sun

Same day

Serum or Plasma     1 – 336 mg/dL
Urine:      3 – 10,080 mg/ dL
 

Urea is the major end product of protein nitrogen metabolism. It is synthesized by the urea cycle in the liver from ammonia which is produced by amino acid deamination. Urea is excreted mostly by the kidneys, but minimal amounts are also excreted in sweat and degraded in the intestines by bacterial action. Determination of blood urea nitrogen is the most widely used screening test for renal function. When used in conjunction with serum creatinine determinations, it can aid in the differential diagnosis of the three types of azotemia: prerenal, renal, and postrenal. Elevations in blood urea nitrogen concentration are seen in inadequate renal perfusion, shock, diminished blood volume (prerenal causes), chronic nephritis, nephrosclerosis, tubular necrosis, glomerular nephritis (renal causes), and urinary tract obstruction (postrenal causes). Transient elevations may also be seen during periods of high protein intake. Unpredictable levels occur with liver diseases.