Hepatitis C Virus Antibody

Message
Order SHCV if test required is HCV Screen.


Test Code
HCV


Alias/See Also
HEPC2G
HEP C


CPT Codes
86803

Preferred Specimen
1.0 mL collected in a SST (serum seprator-gold top tube)


Minimum Volume
0.5 mL


Other Acceptable Specimens
Tiger top (SST)
Gold top (SST)
Red top
Plasma – Li Heparin (PST)
Plasma – Na Heparin
Plasma –EDTA (Lavender)


Transport Temperature
Room temperature


Specimen Stability
Room Temperature: 3 days at 25°C
Refrigerated: 7 days at 2-8°C
Frozen: 3 months at ­20°C
The samples may be frozen and thawed up to 6 times.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples not labeled with complete first and last name and date of birth.
 Hemolyzed samples.
Samples collected in sodium citrate plasma


Methodology
Electrochemiluminescence immunoassay

Setup Schedule
Sun - Sat


Report Available
Same day


Reference Range
Non-reactive


Clinical Significance
The qualitative detection of total antibodies to hepatitis C virus (anti-HCV) in human adult and pediatric ages 18 months through 21 years) serum or plasma. Assay results, in conjunction with other laboratory results and clinical information, may be used to aid in the presumptive diagnosis of HCV infection in persons with signs and symptoms of hepatitis and in persons at risk for hepatitis C infection. The test does not determine the state of infection or associated disease.
Hepatitis C virus, first identified in 1989, is the most common cause of posttransfusion and community-acquired non-A, non-B hepatitis worldwide. Hepatitis C is primarily transmitted through contaminated blood and blood products and to a lower extent by human body secretions.
Infection with HCV frequently leads to chronic hepatitis and cirrhosis, and is associated with the development of hepatocellular carcinoma. Common extrahepatic manifestations comprise mixed cryoglobulinemia and rheumatic diseases. Hepatitis C virus is an enveloped, positive-sense single-stranded RNA virus which has been classified as a genus in the family of Flaviviridae. Like other RNA viruses, the HCV genome exhibits substantial heterogeneity as a result of mutations that occur during viral replication.


Performing Laboratory
Frederick Health Laboratory
400 W 7th Street
Frederick, MD 21701


Last Updated: May 12, 2020


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.