Hepatitis B Surface Ag

Message
This will reflex to the confirmation.


Test Code
HBSAG


Alias/See Also
Hepatitis B Surface Antigen
HBSAG


CPT Codes
87340

Includes
Reactive specimens will be forwarded for confirmation using a Hepatits B Surface Ag confirmatory assay.


Preferred Specimen
1.0 mL collected in a SST (serum seprator-gold top tube)


Minimum Volume
1.0 mL


Other Acceptable Specimens
Tiger top (SST)
Gold top (SST)
Red top
Plasma – Na Heparin, Li Heparin
Plasma –EDTA (Lavender


Transport Temperature
Room Temperature


Specimen Stability
Room Temperature: 6 days at 20-25°C
Refrigerated: 14 days at 2-8°C
Frozen: 6 months at ­20°C
The samples may be frozen and thawed up to 6 times.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Samples not labeled with complete first and last name of patient and date of birth.
Grossly hemolyzed.




Methodology
Electrochemiluminescence immunoassay

Setup Schedule
Sun - Sat


Report Available
Same day


Reference Range
Nonreactive
NOTE: Reactive specimens will be forwarded for confirmation using a Hepatits B Surface Ag confirmatory assay.


Clinical Significance
use for the in vitro qualitative detection of hepatitis B surface antigen (HBsAg) in human serum and plasma. Assay results, in conjunction with other serological and clinical information, may be used for the laboratory diagnosis of individuals with acute or chronic hepatitis B. In addition, this assay may be used to screen for hepatitis B infection in pregnant women to identify neonates at high risk of acquiring HBV during the perinatal period.
The hepatitis B surface antigen, a polypeptide of varying size, is a component of the external envelope of the hepatitis B virus particle (HBV). The blood of persons infected with HBV contains, in addition to intact infectious HBV particles, smaller non-infectious “empty” envelope particles, which are formed in great excess and also contain the hepatitis B surface antigen. The HBsAg determinant a, against which the immune response is mainly directed, is common to all HBsAg particles. In addition, either the main determinants d or y and w or r are present.
The detection of HBsAg in human serum or plasma indicates an infection by the hepatitis B virus. HBsAg is the first immunological marker and is generally present some days or weeks before clinical symptoms begin to appear. In rare cases an HBV infection can also take place without HBsAg being detectable. HBsAg tests are used within the scope of diagnostic procedures to identify persons infected with HBV and to prevent the transmission of the hepatitis B virus.


Performing Laboratory
Frederick Heallth Laboratory
400 W 7th Street
Frederick, MD  21701


Last Updated: May 8, 2020


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.