VANCOMYCIN TROUGH

Message

Collection time MUST be documented on tube or requisition.

Test Code

VANCT

CPT Codes
80202

Includes

Specimen collected prior to dose per facility policy

Preferred Specimen

1.0 mL Plasma Li Heparin

Minimum Volume

0.1 mL

Other Acceptable Specimens

Plasma- EDTA (Lavender)
Serum- Red Top
Serum- SST or Tiger Top

Specimen Stability

Room Temperature: 48 hours at 20-25°C
Refrigerated: 14 days 2-8°C
Frozen: 12 months at -20 °C. Freeze only once

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Samples not labeled with First and Last Name and date of birth.
Grossly hemolyzed specimen

Methodology
Immunoassay

Setup Schedule

24/7

Report Available

Daily

Reference Range

No reference range established for random samples.
Therapeutic trough 10- 20 ug/mL
Therapeutic peak 20-40 ug/mL

Clinical Significance

Vancomycin is a complex glycopeptide antibiotic, which has been used to treat penicillinase-producing staphylococci. It is the drug of choice for the treatment of methicillin and related beta lactam antibiotic resistant Staphylococcus aureus as well as for the treatment of serious gram-positive infections where allergies to penicillin or cephalosporin play a role. Vancomycin is also used in the treatment of antibiotic-induced enterocolitis associated with Clostridium difficile and streptococcal or enterococcal endocarditis, the latter in conjunction with an aminoglycoside, when penicillin or ampicillin is not an option. Monitoring of peak and trough serum or plasma levels is necessary due to potentially serious side effects including ototoxicity, nephrotoxicity, phlebitis, and reversible neutropenia.

Performing Laboratory

Frederick Memorial Hospital
400 W 7th St
Frederick, MD. 21701

Last Updated: August 20, 2019

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.