VANCOMYCIN RANDOM

Message

Collection time MUST be documented on tube or requisition.

Test Code

VANC

Alias/See Also

VANCR

CPT Codes
80202

Preferred Specimen

1.0 mL Serum Red Top

Patient Preparation
Usual sampling time varies dependent upon desired measurement of peak or trough values.

Minimum Volume

0.1 mL

Other Acceptable Specimens

EDTA (Lavender)
Serum- SST or Tiger Top
Plasma Li Heparin

Specimen Stability

Room Temperature: 48 hours at 20-25°C
Refrigerated: 14 days 2-8°C
Frozen: 12 months at -20 °C. Freeze only once.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Samples not labeled with First and Last Name and date of birth.
Grossly hemolyzed specimen.

Methodology
Immunoassay

Setup Schedule

24/7

Report Available

Same day

Reference Range

No reference range established for random samples.
Therapeutic trough 10- 20 ug/mL
Therapeutic peak 20-40 ug/mL

Clinical Significance

Vancomycin is a complex glycopeptide antibiotic, which has been used to treat penicillinase-producing staphylococci. It is the drug of choice for the treatment of methicillin and related beta lactam antibiotic resistant Staphylococcus aureus as well as for the treatment of serious gram-positive infections where allergies to penicillin or cephalosporin play a role. Vancomycin is also used in the treatment of antibiotic-induced enterocolitis associated with Clostridium difficile and streptococcal or enterococcal endocarditis, the latter in conjunction with an aminoglycoside, when penicillin or ampicillin is not an option. Monitoring of peak and trough serum or plasma levels is necessary due to potentially serious side effects including ototoxicity, nephrotoxicity, phlebitis, and reversible neutropenia.

Performing Laboratory
Frederick Memorial Hospital
400 W 7th St
Frederick, MD. 21701

Last Updated: November 1, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.