Antimicrobial Susceptibility, Nocardia/Aerobic Actinomycetes, MIC

Test Code

NOCSTREP

Quest Code

90396

CPT Codes
87186

Includes

Amikacin, Amoxicillin/Clavulanate, Ceftriaxone, Ciprofloxacin, Clarithromycin, Doxycycline, Imipenem, Linezolid, Minocycline, Moxifloxacin, Tobramycin, Trimethoprim/Sulfamethoxazole

Preferred Specimen

Pure culture of Nocardia spp., or other aerobic actinomycetes safely contained (including but not limited to: Rhodococcus, Gordonia, Tsukamurella, Streptomyces), submitted in appropriate culture media on a slant or plate, safely contained

Instructions

In order to perform susceptibility testing and to interpret test results, the identification of the isolate is required.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 90 days determined by viability
Refrigerated: 90 days determined by viability
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Mixed cultures or organisms not considered Nocardia or aerobic actinomycetes • Raw specimens • Frozen isolates • Isolates overgrown with bacteria, yeast, or Fungi

Methodology
Broth Microdilution

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Set up: Mon, Tues, Fri; Report available: 18-19 days

Reference Range

See Laboratory Report

Clinical Significance

Rapidly growing mycobacteria and Nocardia/aerobic actinomycetes can cause a variety of serious infections, particularly in immunocompromised patients. Resistance, toxicity, intolerance, and therapeutic failures may occur with traditional empiric treatment with drugs of choice. Antimicrobial susceptibility testing, especially with newer agents, may help to guide appropriate therapeutic choices.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: October 4, 2017

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.