Coxsackie A Antibodies, CSF

Test Code

19895

CPT Codes
86317 (x6)

Includes

Coxsackie Antibodies A2, A4, A7, A9, A10, A16

Preferred Specimen

2 mL CSF collected in a sterile, leak-proof container

Minimum Volume

0.5 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly icteric

Methodology
Complement Fixation (CF)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Tues-Sat; Report available: 3-6 days

Reference Range

Coxsackie A2 Ab	<1:1 titer
Coxsackie A4 Ab	<1:1 titer
Coxsackie A7 Ab	<1:1 titer
Coxsackie A9 Ab	<1:1 titer
Coxsackie A10 Ab	<1:1 titer
Coxsackie A16 Ab	<1:1 titer

Interpretive Criteria

<1:1	Antibody Not Detected
≥1:1	Antibody Detected

Clinical Significance

Detection of intrathecally-produced organism-specific antibodies in CSF indicates central nervous system infection. However, serum levels of organism-specific antibodies, blood-brain barrier integrity, and possible CSF contamination by blood should be considered when assessing CSF results.

Performing Laboratory
Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

Last Updated: October 28, 2025

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.