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2958 ALUMINUM
Test CodeALUMINU
Preferred Specimen
2 mL serum collected in a no additive, trace element (royal blue-top) tube
Minimum Volume
0.7 mL
Other Acceptable Specimens
Plasma collected in: EDTA or sodium heparin (royal blue-top) tube
Instructions
Draw one royal blue-top tube of blood and discard. Draw second royal blue-top tube. Allow to clot in an upright position. Centrifuge and pour (do not pipette) the serum or plasma into a acid-washed or trace metal-free tube.
Transport Container
Plastic screw-cap vial, acid-washed, or metal-free
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 14 days
Frozen: 30 days
Refrigerated: 14 days
Frozen: 30 days
Methodology
Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Limitations
This measure is very sensitive to aluminum containing medications, e.g., aluminum-containing antacids, and may continue to test as elevated for a prolonged period of time after the medication is stopped.
Clinical Significance
Individuals undergoing hemodialysis are at risk for aluminum toxicity. Prolonged accumulation may cause anemia, encephalopathy, and vitamin D-resistant osteomalacia. Also, workers exposed to high levels or to long-term low levels of aluminum dust are at increased risk of toxicity.