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Fluoxetine
Test Code8389
CPT Codes
80299
Includes
Norfluoxetine, Fluoxetine and Total
Preferred Specimen
1 mL serum
Patient Preparation
Collect at steady-state trough concentration. Specimen should be collected >12 hours after dose.
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), sodium heparin (green-top), or lithium heparin (green-top) tube • Serum collected in a no additive (royal blue-top) tube
Instructions
Do not use gel barrier/serum separator tubes.
Transport Container
Plastic screw-cap vial
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 5 days
Frozen: 30 days
Refrigerated: 5 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gel barrier/Serum Separator Tube (SST®)
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues, Sat a.m.; Report available: 3-6 days
Reference Range
Total | 300-1150 mcg/L |
Clinical Significance
Fluoxetine is an antidepressant drug that is also used in the treatment of bulimia nervosa and obsessive-compulsive disorder. Therapeutic drug monitoring is useful to optimize dose and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386