19911A>G Mutation Analysis

Test Code
16533


CPT Codes
81400

Preferred Specimen
5 mL whole blood collected in an EDTA (lavender-top) tube


Minimum Volume
3 mL


Other Acceptable Specimens
Whole blood collected in: ACD solution A or B (yellow-top) tube, or lithium or sodium heparin (green-top) tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable


Methodology
Capillary Electrophoresis • Fluorescence Detection • Polymerase Chain Reaction Amplification • Single Nucleotide Extension

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Thurs; Report available: 8 days


Reference Range
See Laboratory Report


Clinical Significance
This test can be used to detect the 19911A→G polymorphism in the prothrombin (Factor II) gene which may modulate the risk of deep vein thrombosis in patients with the G20210A mutation.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.