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Cryptococcus Antigen, Serum or Spinal Fluid
Test Code404
CPT Codes
87327
Preferred Specimen
Submit only 1 of the following specimens:
Serum
Container/Tube: Plain, red-top tube(s)
Specimen Volume: 2 mL of serum
Note: 1. Indicate serum. 2. Label specimen appropriately (serum).
Spinal Fluid
Container/Tube: Sterile vial(s)
Specimen Volume: 2 mL of spinal fluid
Note: 1. Indicate spinal fluid. 2. Label specimen appropriately (spinal fluid).
Serum
Container/Tube: Plain, red-top tube(s)
Specimen Volume: 2 mL of serum
Note: 1. Indicate serum. 2. Label specimen appropriately (serum).
Spinal Fluid
Container/Tube: Sterile vial(s)
Specimen Volume: 2 mL of spinal fluid
Note: 1. Indicate spinal fluid. 2. Label specimen appropriately (spinal fluid).
Transport Temperature
Ambient
Methodology
Latex Agglutination
Setup Schedule
Monday through Sunday
Reference Range
Negative
If positive, results are titered.
Critical value (automatic call-back): all positives
If positive, results are titered.
Critical value (automatic call-back): all positives
Clinical Significance
Useful for detecting polysaccharide antigens associated with Cryptococcus neoformans infections. This test has a much greater sensitivity than the India Ink wet mount. Fungal cultures should also be performed in patients who are suspected of having cryptococcosis. Determination of antigen concentration by 2-fold serial dilutions (titer) is useful to monitor response to therapy during the course of Cryptococcus meningitidis
Performed By
CoxHealth
