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Herpes Simplex Virus 1/ 2 IgG HerpeSelect® Type-Specific Antibody
Test CodeHSIGG
Preferred Specimen
1 mL serum (0.2 mL minimum).
Instructions
Specimen may be collected in an SST red top glass tube and transferred to plastic for transport. Do not submit glass tubes.
Transport Container
SST or Red Top Tube
Transport Temperature
Refrigerated, stable 1 week
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Glass tubes
Methodology
Enzyme Immunoassay, Type Specific
Clinical Significance
Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients.