AFP Profile Four

Test Code
AFP4


Includes
Alpha-fetoprotein, Unconjugated Estriol, Human chorionic gonadotrophin, Dimeric Inhibin A


Preferred Specimen
4 ml serum


Instructions
Requires completed FBR requisition, Drawn 15 - 25 weeks gestation


Transport Container
SST tube, 2 tubes


Transport Temperature
Separated serum stable for 7 days refrigerated


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed


Reference Range
See report


Clinical Significance
The levels of these four analytes are related to risk for open fetal defects such as spina bifida, anencephaly, gastroschisis, and omphalocele as well as to risk for Down syndrome (trisomy 21) and trisomy 18.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.