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AFP Profile Four
Test CodeAFP4
Includes
Alpha-fetoprotein, Unconjugated Estriol, Human chorionic gonadotrophin, Dimeric Inhibin A
Preferred Specimen
4 ml serum
Instructions
Requires completed FBR requisition, Drawn 15 - 25 weeks gestation
Transport Container
SST tube, 2 tubes
Transport Temperature
Separated serum stable for 7 days refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed
Reference Range
See report
Clinical Significance
The levels of these four analytes are related to risk for open fetal defects such as spina bifida, anencephaly, gastroschisis, and omphalocele as well as to risk for Down syndrome (trisomy 21) and trisomy 18.