Levetiracetam, Immunoassay

Test Code

KEPRA

CPT Codes
80177

Preferred Specimen

1 mL serum collected in a red-top tube (no-gel)

Patient Preparation
If Brivaracetam has been prescribed, order test code 15142 for Levetiracetam by LC/MS/MS.

Optimum time to collect sample: 0.5 to 1 hour pre-oral dose, trough at steady state (2 weeks after onset of treatment).

Minimum Volume

0.5 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, sodium heparin (green-top) tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 21 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimens collected in gel barrier tubes (SST • PST) • Unspun red-top tube (no-gel)

Methodology
Immunoassay (IA)

Setup Schedule

Sets up 6 days a week.

Report Available

Reports in 2 to 3 days.

Reference Range

6.0-46.0 mcg/mL

Clinical Significance

LEV is currently used as an anti-epileptic drug for the treatment of adult partial seizures particularly as an add-on therapy for refractory patients. It also has potential for other anxiety and cognitive disturbances.

Performing Laboratory
Quest Diagnostics Valencia Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

Last Updated: January 9, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.