A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Porphyrins, Fractionated, Quantitative, 24-Hour Urine [729]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page
If you have any questions regarding these results, please contact the Quest Diagnostics Biochemical Genetics Laboratory at 1-800-642-4657 Ext. 4817 or Ext. 4423 and ask to speak with the laboratory director on call. For general questions about Quest Diagnostics genetic testing, please call the Gene Info line at 1-866-GENE-INFO.
If you have any questions regarding these results, please contact the Quest Diagnostics Biochemical Genetics Laboratory at 1-800-642-4657 Ext. 4817 or Ext. 4423 and ask to speak with the laboratory director on call. For general questions about Quest Diagnostics genetic testing, please call the Gene Info line at 1-866-GENE-INFO.
Test Code
PORPHF
Alias/See Also
729
CPT Codes
84120
Includes
Coproporphyrin I, Coproporphyrin III, Heptacarboxyporphyrin, Hexacarboxyporphyrin, Pentacarboxyporphyrin, Uroporphyrin I, Uroporphyrin III, Total Porphyrins
CPT code 81050 may be added at an additional charge for volume measurement
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
2 mL urine from a 24-hour urine collected in a 5 g sodium carbonate container or no preservative container - protected from light
Minimum Volume
1 mL
Other Acceptable Specimens
No preservative - See Collection Instructions
Instructions
2 mL 24-hour urine in 5 g sodium carbonate container or no preservative container 24-hour urine collected with 5 grams of sodium carbonate, refrigerated and protected from light during collection is preferred.
Collection with no preservative is acceptable, if properly refrigerated and light protected. 24-hour total volume must be provided on the test request form.
Collection with no preservative is acceptable, if properly refrigerated and light protected. 24-hour total volume must be provided on the test request form.
Transport Container
Transport tube - protected from light
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received room temperature • Not protected from light • pH <4.0
Methodology
High Performance Liquid Chromatography (HPLC)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues-Sat; Report available: 1-5 days
Reference Range
Uroporphyrin I | 4.1-22.4 mcg/24 h |
Uroporphyrin III | 0.7-7.4 mcg/24 h |
Heptacarboxyporphyrin | ≤3.3 mcg/24 h |
Hexacarboxyporphyrin | ≤10 mcg/24 h |
Pentacarboxyporphyrin | ≤4.6 mcg/24 h |
Coproporphyrin I | 7.1-48.7 mcg/24 h |
Coproporphyrin III | 11.0-148.5 mcg/24 h |
Total Porphyrins | 35.0-210.7 mcg/24 h |
Clinical Significance
Porphyria is a group of distinct disorders characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin Fractionation of Urine is useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |
Last Updated: December 6, 2021