Clonazepam [340]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
CLONZ


Alias/See Also
340


CPT Codes
80346 (HCPCS: G0480)

Preferred Specimen
 2 mL serum collected in a red-top tube (no gel)


Patient Preparation
Collect at trough concentration, immediately before the administration of the next dose

Minimum Volume
1 mL


Other Acceptable Specimens
Serum collected in a no additive (royal blue-top) tube • Plasma collected in an: EDTA (lavender-top), or (royal blue-top), or sodium heparin or lithium (green-top) tube


Transport Container
Plastic screw-cap vial


Transport Temperature
Frozen 


Specimen Stability
Room temperature: 24 hours
Refrigerated: 72 hours
Frozen: 14 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gel barrier/Serum Separator Tube (SST®)


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues, Thurs, Sat p.m.; Report available: 2 days


Reference Range
30-60 mcg/L


Clinical Significance

Clonazepam is a benzodiazepine used as a tranquilizer. Clonazepam is used in treating patients with seizures and in reducing tardive dyskinesia. Therapeutic drug monitoring is useful to avoid toxicity.



Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Last Updated: November 29, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.