Parainfluenza Virus (Types 1, 2, 3 and 4) RNA, Qualitative, Real-Time PCR

Test Code
PINFLU


CPT Codes
87631

Preferred Specimen
Nasopharyngeal or oropharyngeal swab submitted in 3 mL M4 media or VCM medium (green-cap) tube, or UTM equivalent or
2 mL bronchial lavage or sputum collected in a plastic sterile leak-proof container


Minimum Volume
0.6 mL


Transport Temperature
Refrigerated (cold packs)


Specimen Stability

Swabs
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days

Bronchial lavage
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Sputum
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days



Methodology
Real-Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)

Setup Schedule
Set up: Mon-Sat; Report available: 2-4 days


Reference Range
Parainfluenza 1 RNA Not detected
Parainfluenza 2 RNA Not detected
Parainfluenza 3 RNA Not detected
Parainfluenza 4 RNA Not detected


Clinical Significance
Human parainfluenza virus (types 1, 2, 3 and 4) are important respiratory pathogens and are major causes of upper and lower respiratory tract diseases. A multiplex Real-Time RT-PCR assay offers the advantages of increased specificity and sensitivity, identification of HPIV type in a single reaction, and rapid availability of the results. All of these factors will assist the clinician in the diagnosis of respiratory disease, decrease inappropriate use of antibiotics, as well as reduce time of hospitalization and help prevent nosocomial infections.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.