Coxsackie B (1-6) Antibodies, Serum

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
CXSCKB


CPT Codes
86658 (x6)

Includes
Coxsackie Antibodies B1, B2, B3, B4, B5, B6


Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Complement Fixation (CF)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days


Report Available
2 - 5 days


Limitations
Culture does not usually support growth of coxsackie A viruses.


Reference Range
Coxsackie B1 Ab<1:8 titer
Coxsackie B2 Ab<1:8 titer
Coxsackie B3 Ab<1:8 titer
Coxsackie B4 Ab<1:8 titer
Coxsackie B5 Ab<1:8 titer
Coxsackie B6 Ab<1:8 titer

Interpretive Criteria
<1:8Antibody Not Detected
≥1:8Antibody Detected


Clinical Significance
Coxsackie B viruses can cause rashes, pharyngitis, meningitis and myocarditis.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Last Updated: November 29, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.