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FISH, Multiple Myeloma, IGH/MAF, t(14;16)
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Test Code
FSHIGH
CPT Codes
88275, 88271 (x2)
Preferred Specimen
3 mL bone marrow collected in transport media
Minimum Volume
1 mL
Other Acceptable Specimens
Bone marrow collected in: sodium heparin (green-top), or sodium heparin (royal blue-top), or sodium heparin lead-free (tan-top) tube
Instructions
1-3 mL bone marrow in transport medium, bone marrow in sodium heparin tube (green-top) is preferred, (royal blue-top, tan-top) are acceptable. Ship at room temperature. Bone marrow transport medium is available upon request.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not reject.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not reject.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: See instructions
Refrigerated: See instructions
Frozen: See instructions
Refrigerated: See instructions
Frozen: See instructions
Methodology
Fluorescence in situ Hybridization (FISH)
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Daily; Report available: 6 days
Reference Range
See Laboratory Report
Clinical Significance
The IGH/MAF translocation, t(14;16), provides important prognostic information in patients with plasma cell myeloma.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: November 29, 2021