Flunitrazepam and Metabolites, Quantitative, Serum

Test Code

FLUNTR

CPT Codes
80346

Includes

Flunitrazepam, 7-Aminoflunitrazepam, and N-Desmethylflunitrazepam

Preferred Specimen

2 mL serum collected in a red-top tube (no gel)

Minimum Volume

1 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 60 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Serum separator tube (SST)

Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Thurs a.m.; Report available: 4 days

Reference Range

Flunitrazepam	<5 ng/mL
7-Aminolunitrazepam	<5 ng/mL
N-Desmethylflunitrazepam	<5 ng/mL

Clinical Significance

In Latin America and Europe, Rohypnol (Flunitrazepam) is prescribed as a short-term treatment for insomnia, and as a preanesthetic medication. Flunitrazepam is considered a drug of abuse when used to enhance the effect of other substances such as marijuana, heroin, and ethanol. The combination of ethanol and flunitrazepam may lead to sedation, loss of motor function, impaired judgement, behavioral changes, and anterograde amnesia.

Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.