Cysticercus Antibody (IgG), Western Blot, Serum

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
CYSTAB


CPT Codes
86682

Preferred Specimen
1 mL serum


Minimum Volume
0.5 mL


Transport Container
Transport tube


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Western Blot (WB)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues, Thurs; Report available: 2-5 days


Reference Range
Negative

Interpretive Criteria
Negative None of 6 specific bands detected
Positive One or more of 6 specific bands detected

This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia solium, the agent causing cysticercosis. Detection of antibodies to any of 6 specific T. solium glycoprotein bands of molecular weights 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reactivity to the 50 and 42-39 glycoprotein bands may reflect cross-reactive antibodies induced by echinococcosis.
A negative test result does not exclude the diagnosis of neurocysticercosis, particularly if only a single brain lesion is present. The sensitivity increases from 50% or less for a solitary brain cyst to greater than 90% if 3 or more cysts are present.


Clinical Significance
This assay is a qualitative test for the confirmation of specific IgG antibodies recognizing Taenia Solium, the agent causing Cysticerosis. Detection of antibodies to any 6 specific T.solium glycoprotein bands of molecular weight 50, 42-39, 24, 21, 18, and 14 kilodaltons is interpreted as a positive result. However, a positive result without reac- tivity to the 50 and 42-39 glycoprotein bands may reflect crossreactive antibodies induced by Echinococcus.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: November 29, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.