Creatine, 24-Hour Urine

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

CPT Codes
82540, 82570


CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen
3 mL urine from a 24-hour collection - no preservative

Minimum Volume
2 mL

Submit 24-hour urine in a plastic, leakproof container. Do not use preservatives. Keep refrigerated during collection. Freeze immediately. Please specify on the request form and on the urine container the total 24-hour urine volume. Freeze and ship frozen.

Transport Temperature

Specimen Stability
Room temperature: 4 hours
Refrigerated: 24 hours
ozen: 90 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Received thawed • Received refrigerated • Received room temperature

Colorimetric (C) • Enzymatic

Setup Schedule
P.M. Sets up 5 days a week.

Reference Range
⁠⁠⁠⁠⁠⁠⁠Creatine, 24-Hour Urine
Male6-56 mg/24hr
Female8-170 mg/24hr

Clinical Significance
Creatine, produced by the liver, is essential for metabolism of the brain and muscles. Creatine is converted to creatinine and excreted.

Performing Laboratory
Quest Diagnostics Chantilly Nichols Institute
14225 Newbrook Dr.
Chantilly, VA 20151-2228

Last Updated: November 29, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.