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C4d Fragment, EIA
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
C4DF
CPT Codes
83520
Preferred Specimen
1 mL frozen plasma collected in an EDTA (lavender-top) tube
Minimum Volume
0.2 mL
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 4 hours
Frozen: 14 days
Refrigerated: 4 hours
Frozen: 14 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis • Serum • Gel barrier interferes with assay methodology
Methodology
Enzyme Immunoassay (EIA)
FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
Setup Schedule
Tuesday Night Report available: 4 Days
Reference Range
0.9-8.0 mcg/mL
Clinical Significance
Clinical use is to exclude known rheumatoid arthritis, systemic lupus erythematosus, and chronic uticaria with hypocomplementemia. C4d is a stable activation product of C4 cleavage, and is useful to determine classical pathway complement activation.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Last Updated: November 24, 2021
