Respiratory Syncytial Virus Antibody, Serum

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

CPT Codes

Preferred Specimen
1 mL serum

Minimum Volume
0.5 mL

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric, lipemic, or hemolyzed samples

Complement Fixation (CF)

Setup Schedule
Set up: Tues-Sat; Report available: 2-5 days

Reference Range
<1:8 titer

Interpretive Criteria
<1:8 Antibody Not Detected
≥1:8 Antibody Detected
Single titers ≥1:64 usually indicate recent titer RSV infection. A four-fold or greater increase in titer between acute and convalescent specimens is required for diagnosis of RSV infection in adults and children >6 months of age. In contrast, titer only about 50% of infected children less than 6 titer months of age exhibit a four-fold or greater increase in titer. Viral isolation and RSV antigen detection methods are recommended for patients <6 months old.

Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

Last Updated: December 6, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.