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Infliximab Quantitation w/Reflex to Antibodies, to Infliximab, Serum
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
INFXR
Alias/See Also
Remicade
CPT Codes
80230, 82397 if appropriate
Preferred Specimen
1 mL serum from a Red Top Tube (SST is NOT acceptable)
Patient Preparation
1. Draw blood immediately before next scheduled dose (trough specimen).
2. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
Minimum Volume
0.5 mL
Instructions
Centrifuge red top within 2 hours of collection. Transfer serum to a pour off tube.
Transport Container
Pour off tube
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature = N/A
Refrigerated = 28 days
Frozen = 28 days
Refrigerated = 28 days
Frozen = 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum from a SST, Gross hemolysis, gross icterus
Methodology
Selective Reaction Monitoring Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS),
Electrochemiluminescent Bridging Immunoassay with Acid Dissociation
Setup Schedule
Monday, Wednesday, Thursday, Friday
Report Available
3 - 6 days
Clinical Significance
Trough level quantitation for evaluation of patients with loss of response to infliximab and infliximab-dyyb
Performing Laboratory
Mayo Clinic Laboratories -- Rochester Superior Drive
3050 Superior Drive NW
Rochester, MN 55901
Last Updated: November 19, 2021
