Infliximab Quantitation w/Reflex to Antibodies, to Infliximab, Serum

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

Alias/See Also

CPT Codes
80230, 82397 if appropriate

Preferred Specimen
1 mL serum from a Red Top Tube (SST is NOT acceptable)

Patient Preparation
1. Draw blood immediately before next scheduled dose (trough specimen).
2. For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins. 

Minimum Volume
0.5 mL

Centrifuge red top within 2 hours of collection. Transfer serum to a pour off tube.

Transport Container
Pour off tube

Transport Temperature

Specimen Stability
Room Temperature = N/A
Refrigerated = 28 days
Frozen = 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum from a SST, Gross hemolysis, gross icterus

Selective Reaction Monitoring Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS),
Electrochemiluminescent Bridging Immunoassay with Acid Dissociation

Setup Schedule
Monday, Wednesday, Thursday, Friday

Report Available
3 - 6 days

Clinical Significance
Trough level quantitation for evaluation of patients with loss of response to infliximab and infliximab-dyyb

Performing Laboratory
Mayo Clinic Laboratories -- Rochester Superior Drive
3050 Superior Drive NW
Rochester, MN 55901

Last Updated: November 19, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.