Chromosome Analysis, Tissue

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

CHRMTS

This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.

*** Test may be replaced by %39650 Cytogenetics Communication and %39667 Chromosome Analysis, Tissue, No Growth ***

5 x 5 tissue collected in a sterile container in Hanks', Ringer's solution or culture medium with antibiotics.

2 x 3 mm

Tissue collected in sterile saline

See Genetics Specimen Collection Section for detailed specimen instructions.
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not Reject.

Room Temperature

Room Temperature = Preferred
Refrigerated = Acceptable
Frozen = Unacceptable

Formalin-fixed

Daily

15 days

See Laboratory Report

Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities, which are associated with approximately one-half of all first trimester spontaneous abortions. Chromosome testing on fibroblasts obtained from a tissue biopsy is performed to investigate tissue specific mosaicism not present in blood lymphocytes. Fresh cells from tissue biopsies obtained postmortem may still be suitable for chromosome analysis when the patient's blood is not available or viable. If chromosome analysis is unsuccessful, please contact the laboratory genetic counselor at 1-866-GENEINFO (1-866-436-3463) to discuss the option of adding chromosomal microarray (CMA) testing.