Chloride, 24-Hour Urine without Creatinine [11314]

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

Alias/See Also

CPT Codes

CPT code 81050 may be added at an additional charge for volume measurement

Preferred Specimen
10 mL of 24-hour urine, unpreserved, submitted in a plastic, leak-proof container

Minimum Volume
2 mL

Other Acceptable Specimens
24-hour urine submitted in a UA Urinalysis Transport Tube (yellow-top, blue fill line preservative tube), or preserved with Boric Acid, Acetic Acid, HCl, and submitted in plastic, leak-proof container

Record total volume and collection time on specimen container and requisition.

Transport Temperature
Room temperature

Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 60 days

Ion Selective Electrode (ISE)

Setup Schedule
Monday-Sunday Morning
Report available: 4 Days

Reference Range
31-260 mmol/24 h

Clinical Significance

Urine chloride excretion approximates the dietary intake. The chloride content of most foods parallels that of sodium. An increase in urine chloride may result from water deficient dehydration, diabetic acidosis, Addison's Disease, and salt-losing renal disease. Decreased urine levels are seen in congestive heart failure, severe diaphoresis and in hypochloremic metabolic alkalosis due to prolonged vomiting.

Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386

Last Updated: November 29, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.