Complement Component C1q [981]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
C1Q


Alias/See Also
981;
C1Q Complement Component;
Component C1Q


CPT Codes
86160

Preferred Specimen
1 mL serum


Minimum Volume
0.1 mL


Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube or PPT (white-top) tube


Instructions
Separate serum within one hour of draw time and refrigerate.
Can be drawn in a gel barrier tube but needs to be separated within one hour from time drawn.


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 4 days
Refrigerated: 10 days
Frozen: 29 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia


Methodology
Radial Immunodiffusion (RID)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily; Report available: 3-7 days


Reference Range
5.0-8.6 mg/dL


Clinical Significance
The complement system is critical to the inflammatory response.  C1q concentrations may be decreased in patients with acquired angioedema, immune complex induced vasculitis, and concurrent low concentrations of C1 inhibitor, carcinoma, or lymphoma.


Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042



Last Updated: November 29, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.