Kappa/Lambda Light Chains,Total, Random Urine [34318]

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Test Code

Alias/See Also

CPT Codes
83883 (x2)

Preferred Specimen
2 mL random urine collected in a plastic leak-proof container, no preservative

Minimum Volume
0.5 mL

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 12 hours
Refrigerated: 7 days
Frozen: 14 days


Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days

Reference Range
Kappa Light Chain <2.00 mg/dL
Lambda Light Chain <2.00 mg/dL

Clinical Significance
Polyclonal immunoglobulin light chains (kappa and lambda) normally occur in a ratio of 2:1, whereas monoclonal immunoglobulin light chains exhibit only one type of light chain, either kappa or lambda. A kappa/lambda ratio outside of 2:1 is an indication of a monoclonal gammopathy.

Performing Laboratory
Quest Diagnostics Nichols Institute
27027 Tourney Road
Valencia, CA 91355-5386

Last Updated: November 30, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.